Mucoadhesion is a type of bioadhesion in which two materials, at least one of which is mucosal, are held together for extended periods by interfacial forces.
To successfully achieve mucoadhesion in pharmaceutical products, the choice of excipient in your formulation is key.
Lubrizol’s Carbopol® polymers and Noveon® polycarbophil are high quality excipients offering superior mucoadhesive performance compared to other polymers. When compared in vitro, study data demonstrates that Carbopol polymers and Noveon polycarbophil provide longer retention times on mucosa than other polymers see Figure 1 for an example and download our tech brief to see more.
Lubrizol’s Carbopol polymers and Noveon polycarbophil:
This technical brief will cover the use of polymers in a variety of dosage forms (buccal/sublingual tablets, liquid, semi-solid formulations, and oral care products) to impart mucoadhesion. The basic mechanism of mucoadhesion and methods to evaluate it in the context of pharmaceutical applications will also be reviewed, also how it can improve and differentiate drug products. Download the brief.
Looking to improve drug product effectiveness and differentiate? Mucoadhesion – the ability of a formulation to adhere to a mucous membrane – is an attractive option for those keen to ensure their products stand out in a crowded market. Read our guide to learn more.