Comparison Overview of Carbopol® and Pemulen™ Polymers for Topical Applications | ||||||
---|---|---|---|---|---|---|
Self Wetting Polymers | Ultrez 10 NF | |
|
|||
Ethyl Acetate Polymers | 974P NF | 971P NF | ||||
Cosolvent Polymers | 5984 EP | 980 NF | 981 NF |
TR-1 NF, TR-2 NF 1, ETD 2020 NF |
||
Traditional Polymers2 | 934 NF,
934P NF |
940 NF | 941 NF | 1342 NF | ||
Properties in a Formulated Application | ||||||
Flow Characteristics | Short | Short | Short | Very Short | Long | Long |
Relative Viscosity | High | High | High | Very High | Low | Medium |
Suspending Ability
(yield value) |
High | High | High | High | High | High |
Mucilage Clarity | High | Medium | Medium | High | High | High |
Relative Ion Tolerance | Low | Low | Low | Low | Medium | High |
Relative Shear Tolerance3 | Medium | Medium | High | High | Low | Low |
Applications | ||||||
Clear Gels | ||||||
Hydroalcoholic Gels | ||||||
Lotions | ||||||
Creams | ||||||
Surfactants Systems | ||||||
High Electrolyte Systems |
1 Pemulen™ Polymers (Pemulen TR-1 NF and TR-2 NF). All other products noted in the table belong to the Carbopol® polymer product family.
2 Traditional polymers are synthesized in benzene. The Carbomers Monograph in the European Pharmacopeia stipulates that benzene is limited to 2 ppm.
3 Prolonged exposure to high shear should be avoided for all carbomers.