The First Peptide for Expression Wrinkles

A breakthrough in cosmetic technology as an alternative to well-known cosmetic procedures, topically targeting the same wrinkle-formation mechanism in a very different way.

Argireline® peptide is a hexapeptide designed to mimic Botulinum Toxin. The peptide destabilizes the SNARE complex, minimizing the fusion of neurotransmitter-loaded vesicles with the neuron membrane. As a consequence, minimal neurotransmitters are released to the synapse and muscle contraction is reduced, creating an anti-wrinkle effect.

Science. The formation of the SNARE protein complex is essential for the acetylcholine release at the synapsis, the neurotransmitter involved in muscle contraction.


Nothing is more attractive than a relaxed face

Effect appears in just 1 week

As demonstrated in vivo, a cream with 2% Argireline® peptide solution decreased appearance of wrinkles: volume diminished by 20.6% and length by 15.9%, on average, with statistically significant results. Other parameters used to describe wrinkles, like roughness and depth, were also decreased as proved in further clinical studies.

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Did you know…? that Argireline® peptide…

  • Is obtained on a solid matrix, a methodology created by professor R. Bruce Merrifield (Rockefeller University, NY, UAA) that in 1884 received the Nobel Prize in chemistry for this development.
  • After more than 10 years of research the peptide was officially launched in 2001.
  • It was a real breakthrough innovation as the first peptide with a specific effect on expression wrinkles. Its mechanism of action has made a significant difference to the industry.
  • Today, Argireline® peptide is still a leader in the cosmetic industry for its proven efficacy in attenuating the appearance of expression wrinkles.

Argireline® peptide
around the world

Millions of users later, we're changing the face of anti-aging again. In the dynamic world of beauty, we weren't simply looking for an evolution, but a revolution. Discover the market's first multifunctional peptide focused on relaxing post-expression..

Reaching New Horizons