Argireline® peptide is a hexapeptide designed to mimic Botulinum Toxin. The peptide destabilizes the SNARE complex, minimizing the fusion of neurotransmitter-loaded vesicles with the neuron membrane. As a consequence, minimal neurotransmitters are released to the synapse and muscle contraction is reduced, creating an anti-wrinkle effect.
Science. The formation of the SNARE protein complex is essential for the acetylcholine release at the synapsis, the neurotransmitter involved in muscle contraction.
As demonstrated in vivo, a cream with 2% Argireline® peptide solution decreased appearance of wrinkles: volume diminished by 20.6% and length by 15.9%, on average, with statistically significant results. Other parameters used to describe wrinkles, like roughness and depth, were also decreased as proved in further clinical studies.
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