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Sustained-Release Caffeine Tablets

Enable your consumers to take control of their energy and focus

Carbopol® polymers are reliable, proven tools for creating high-value nutraceutical products.

Sustained release caffeine tablets formulated with Carbopol polymers offer key features and benefits for consumers:

  • Smaller, easier-to-swallow tablets
  • Optimized delivery (up to 12 hours in vitro)
  • Stable, consistent delivery without a crash
  • Consistent dosing from tablet-to-tablet
  • Compatible with multiple strengths (100 and 200 mg)

Caffeine Sustained Release Tablets with Carbopol Polymers

Materials and Methods

Property Value
Sustained Release Polymers Carbopol® 971P NF Polymer
Carbopol® 71G NF Polymer
Carbopol Polymer Inclusion Level 5 to 25%
CaffeineC Strength 100 and 200 mg
Manufacturing Method Direct Compression


  • Carbopol Polymers enabled 8 to 12 hours of in vitro caffeine release
  • Sustained release was achieved with as little as 3% Carbopol 971P NF polymer
  • Good control over release was demonstrated at 100 mg and 200 mg strengths
  • Performance was maintained in simulated stomach and small intestine
Caffeine Release from 100mg and 200mg Tablets in 0.1N HCl (Stomach)
Caffeine Release from 100 mg and 200 mg Tablets in pH 6.8 Phosphate Buffer (Intestines)

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