Lubrizol’s Apinovex™ polymers are high molecular weight polyacrylic acid excipients for enhanced spray-dried amorphous solid dispersions (ASDs). Apinovex excipient enhances the solubility of BCS Class II and IV APIs and facilitates more efficient oral dosage forms with high, stable drug loading.

This novel excipient offers:

High, stable drug loading (up to 80%) via spray drying
Significantly improved drug release profile compared to crystalline APIs
IP protection and 505(b)(2) formulations/lifecycle management

Effective Dosages in Smaller Tablet Sizes