Imagine a world where wrinkles could be diminished without the need for injections or toxins. In the late 1980s, Lipotec™ Active Ingredients, part of Lubrizol Beauty, set out to make this dream a reality with the development of the Argireline^® peptide.

The Origin of Argireline^® peptide and its impact on the Cosmetic Industry

Creating Argireline^® peptide was no easy feat. It required over a decade of dedicated research by a multidisciplinary team of scientists. Using rational design, they crafted a peptide that mimicked the structure and function of SNAP-25, a crucial protein in muscle contraction.

Argireline^® peptide revolutionized the cosmetic industry by being the first peptide on the marketplace that could reduce muscle contractions topically, offering an alternative to invasive and toxin-based methods. With over two decades on the market, it became a staple ingredient for many brands, known for visibly reducing wrinkle appearance in just one week.

Development of Argireline^® Amplified peptide

With a new generation of consumers demanding greater efficacy, Lubrizol Beauty aimed to create an amplified version of Argireline^® peptide that would exceed all expectations.

The team returned to the drawing board, using different approaches to create a library, this time of hundreds of thousands of peptide sequences. The scientists used digital technologies to predict the efficacy against the selected target, which was validated by extensive in vitro and ex vivo testing to ultimately identify the best-performing peptide. 3D skin models and collaborations with renowned research groups ensured that the results would translate into real-life effects.

The Result: a new and amplified peptide

After years of dedication, Lubrizol unveiled Argireline^® Amplified peptide, an evolution of the original peptide with a different sequence and superior activity demonstrated both in vitro and in vivo. This new peptide represents a significant breakthrough in the fight against the signs of aging.

The evolution from Argireline^® peptide to Argireline^® Amplified peptide showcases Lubrizol’s unwavering commitment to scientific innovation in cosmetics. By combining scientific expertise, innovative testing methods, and a relentless pursuit of excellence, at Lubrizol we have unleashed the power of Argireline^® Amplified peptide, proving that in the quest for youthful, wrinkle-free skin, the possibilities are limitless.

Innovation and Revolution: The Journey to Argireline® Amplified Peptide