Incorporation of Dexamethasone into Silicone Drug-Device Combination Products

In recent years, there has been increased interest in incorporating dexamethasone into medical devices. A device containing dexamethasone can help decrease inflammation, suppress the body’s natural immune response to foreign objects, and reduce the size of the fibrous capsule that forms after implantation. Dexamethasone’s low protein affinity and long half-life allow it to provide long-lasting anti-inflammatory effects, making the drug an attractive option for long-term implants that need continuous protection against inflammation.

Download our whitepaper to learn why development of implantable devices or combination products should include an evaluation of silicone-dexamethasone:

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