In the competitive world of beauty and skin care, few names have garnered as much respect and trust as the Argireline® peptides. This powerful family of active ingredients has gained global recognition, featured in over 2,500 products and embraced by nearly 30%* of the top 10 global beauty companies. Renowned brands rely on Argireline® peptides to deliver visible results, making it a favorite among consumers and skin care professionals alike.

What Makes Argireline® peptide So Special?

Since its launch in 2000, Argireline® peptide quickly established itself as one of the world's most acclaimed anti-wrinkle ingredients. Its effectiveness lies in its unique ability to emulate the biological pathway of Botulinum toxin type A (BTA) injections by disrupting the SNARE complex assembly, thereby decreasing acetylcholine release. This helps to reduce the appearance of wrinkles and fine lines, providing smoother, younger-looking skin.

In 2020, Lubrizol launched Argireline® Amplified peptide, an evolution of the historical Argireline® peptide with superior activity and added muscle relaxation effects. Also reducing the appearance of age related changes in all skin layers for a multifunctional effect to globally enhance the skin appearance.

Argireline® Amplified peptide earned the 2022 Allē Award for Most Significant Anti-Aging Active, reinforcing its reputation for innovation and effectiveness in skincare.

A recent clinical studies have demonstrated that Argireline® Amplified peptide not only helps mimic the effect of BTA injections, but also can helpsignificantly extend their effects by 8 weeks.

Launched in 2023, Argireline® YOUth peptide was specifically developed for formulation into oil-based products such as makeup and sticks. Our tests on products frequently used by younger consumers in their daily skin care routines revealed impressive results. The peptide effectively minimized the appearance of expression lines without compromising natural facial expressions, reduced the visibility of wrinkles around the eyes, and smoothed the skin in the nasolabial and forehead regions. Additionally, it significantly diminished the appearance of "tech neck" lines, making it a versatile and powerful ingredient for maintaining youthful skin.

The Buzz Around Argireline® peptide

Since its market debut, Argireline® peptide has gained widespread popularity thanks to its innovative mechanism and high effectiveness. Over the years, its popularity has continued to grow. In the past year, Argireline® peptide has garnered significant attention among Google users in the US, with an impressive average of 18.8k monthly searches.** This surge in interest is mirrored in online beauty conversations, where the focus on prevention and maintaining youthful skin through skin care products, rather than Botulinum Toxin, has become increasingly prominent. The hashtag #betterthanbotox has seen a remarkable 620% year-over-year growth in engagement actions, highlighting a growing trend towards non-invasive skin care solutions.***

Loved by both the industry's leading beauty brands and consumers, Argireline® peptides remain an essential part of beauty routines and continue to conquer new generations.

*Source: Mintel GNPD-Jan 2025
**Source: SPATE US Search - from Apr 2024 to Mar 2025
*** Source: Radarly Social Listening Platform – April 2024 to March 2025 vs April 2023 to March 2024

Argireline® peptides: Trusted by Top Beauty Brands Worldwide