The beauty of peptides

Peptides are highly valued in the cosmetic industry for their unique properties and their ability to interact with specific biological receptors. For over 20 years, Lubrizol has been at the forefront of developing cosmetic peptides. However, traditional synthetic techniques may not fully align with today’s environmental sustainability goals. While the environmental impact of formulating with peptide active ingredients is relatively minor, it is essential for ingredient suppliers, formulators, and brands to work towards minimizing their ecological footprint.

A greener approach to peptide synthesis

Recent advancements in peptide synthesis have made a more sustainable approach possible. Argireline^® Amplified peptide was the first naturally-derived anti-aging cosmetic peptide developed by Lubrizol, addressing green chemistry principles. Argireline^® Amplified peptide utilizes natural amino acids from renewable sources, predominantly derived through sugar fermentation, avoiding synthetic modifications.

Biodegradability and environmental impact

Biodegradability is another important aspect of sustainable active ingredients. Argireline^® Amplified peptide is readily biodegradable, according to OECD 301 A, thanks to its bio-compatible sequence. This means the peptide does not accumulate in nature and releases environmentally friendly components.

Innovative manufacturing processes

Lubrizol has made significant modifications with the manufacturing process of Argireline^® Amplified peptide to address green chemistry principles. This includes reducing the use of organic solvents by approximately 15%, replacing hazardous reagents, and minimizing or eliminating certain synthetic steps. Automated solvent delivery and real-time monitoring of critical reaction parameters enhance safety and reduce waste generation.

Efficacy without compromise

Despite being naturally derived and addressing green chemistry principles, Argireline^® Amplified peptide does not compromise on efficacy. Studies show thatit outperforms Argireline^® peptide in attenuating neuronal exocytosis. Clinically, Argireline^® Amplified peptide has been shown to help the skin appear 5 years younger in just 5 days. This innovation highlights Lubrizol’s ability to create naturally derived and sustainable peptides without compromising on exceptional skin care efficacy.

The future of sustainable peptides

Following the success of Argireline^® Amplified peptide, the Lubrizol team introduced Uplevity™ e-Lift peptide, also addressing green chemistry principles. This achievement demonstrates Lubrizol's commitment to creating sustainable and effective peptides. It paves the way for future peptide development, emphasizing renewable resources, biodegradable components, and optimized manufacturing processes,

With a commitment to performance and environmental responsibility, Lubrizol’s scientists are dedicated to pushing the boundaries of peptide research. Through green chemistry, Lubrizol aims to create a new generation of peptides that deliver outstanding skin care benefits while contributing to a greener and more sustainable world.

A New Era in Beauty: Sustainable Peptides and Green Chemistry