Pharmaceutical Ingredients

Noveon® AA-1 Polycarbophil

Suitable applications: Oral and topical
Residual solvent: Ethyl acetate

Noveon AA-1 Polycarbophil, USP is a high molecular weight acrylic acid polymer crosslinked with divinyl glycol. It provides excellent bioadhesive properties and has been used extensively to enhance the delivery of active ingredients to various mucous membranes. Noveon® AA-1 Polycarbophil can be used for the formulation of buccal, vaginal, nasal ophthalmic and rectal bioadhesive products.

Noveon® AA-1 Polycarbophil can also be used as a controlled release agent in oral solid dosage applications. Typical usage levels for achieving extended release characteristics in tablets manufactured by aqueous granulation are 5 – 10 wt.%, depending on the drug properties, co-excipients and processing parameters.